Activation Markers CD63 and CD203c Are Upregulated in Chronic Urticaria
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چکیده
منابع مشابه
Activation Markers CD63 and CD203c Are Upregulated in Chronic Urticaria
522 Ann Dermatol Received November 15, 2012, Revised January 25, 2013, Accepted for publication January 28, 2013 Corresponding author: Hans Jürgen Hoffmann, Allergy Center for West Denmark, Department of Pulmonary Medicine, Health: Aarhus University, Building 2b, Nørrebrogade 44, DK 8000 Aarhus C, Denmark. Tel: 45-78462107, Fax: 45-78462110, E-mail: hans.jurgen.hoffmann @ki.au.dk This is an Ope...
متن کاملComparison of two basophil activation markers CD63 and CD203c in the diagnosis of amoxicillin allergy.
BACKGROUND To confirm allergy to beta-lactam (BL), a basophil activation test in flow cytometry based on CD63 up-regulation was described. CD203c is a more recent basophil activation marker and up to day there is no consensus about which marker is the more sensitive one. CD203c has not yet been evaluated in the diagnosis of BL allergy. OBJECTIVE The aim of the study was to compare the reliabi...
متن کاملPositive CD63 Basophil Activation Tests Are Common in Children with Chronic Spontaneous Urticaria and Linked to High Disease Activity.
BACKGROUND The basophil activation test (BAT) using CD63 expression is a sensitive and specific tool for the diagnostic workup of autoimmune chronic spontaneous urticaria (CSU). The definition of a positive BAT is directly dependent on the reference range and the cutoff values established in control populations. As of now, the pediatric reference range and cutoff values of the CD63 BAT remain t...
متن کاملBasophil Markers for Identification and Activation in the Indirect Basophil Activation Test by Flow Cytometry for Diagnosis of Autoimmune Urticaria
BACKGROUND The indirect basophil activation test using flow cytometry is a promising tool for autoimmune urticaria diagnosis. We aimed to identify better donor basophils (from atopic vs. non-atopic donors and interleukin-3 primed vs. unprimed basophils) and improve basophil identification and activation markers (eotaxin CC chemokine receptor-3 [CCR3] vs. CD123 and CD63 vs. CD203c). METHODS Do...
متن کاملIncreased Level of Basophil CD203c Expression Predicts Severe Chronic Urticaria
Increased FcεR1α expression with upregulated CD203c expression on peripheral basophils is seen in patients with chronic urticaria (CU). However, there has been no published report on the association between CD203c expression level and clinical disease activity in CU patients. To investigate whether the increase of basophil activation is associated with the disease activity of CU, we measured ba...
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ژورنال
عنوان ژورنال: Annals of Dermatology
سال: 2013
ISSN: 1013-9087,2005-3894
DOI: 10.5021/ad.2013.25.4.522